2023_Technolution_Leaderboard

WEARABLES

LOW-COMPLEXITY, EASY-TO-USE WEARABLE INJECTION PLATFORM

Jesper Roested discusses the increasing prevalence of biologics formulated for large-volume injections in drug development and how wearable devices, including Subcuject’s offering, may be a better solution for delivering these drugs than scaled-up conventional autoinjectors.

REDUCE PHARMA DEVELOPMENT TIME: LARGE-VOLUME SUBCUTANEOUS DELIVERY WITH THE ENFUSE^®

Mehul Desai discusses how Enable Injections' enFuse^® delivery system provides a flexible alternative for subcutaneous administration of high-volume therapeutics.

HOW PATIENT & TREATMENT FACTORS SHAPE SUBCUTANEOUS DOSING PREFERENCES

Dr Andreas Schneider

HOW PATIENT & TREATMENT FACTORS SHAPE SUBCUTANEOUS DOSING PREFERENCES

Andreas Schneider highlights the importance of understanding the drivers of dosing preferences when it comes to choosing the right injection device for patients. Specifically, the research summarised here studies whether and how patient characteristics and treatment attributes influence the decision to use prefilled handheld autoinjectors or large-volume wearable injectors.

ENABLING DRUG DEVELOPMENT THROUGH DRUG DELIVERY MANUFACTURING

Dr Andrei Yosef

ENABLING DRUG DEVELOPMENT THROUGH DRUG DELIVERY MANUFACTURING

Andrei Yosef looks at the role of manufacturing in the development of drug delivery devices and highlights the benefits of the company’s Sorrel device, which enables pharma companies to experiment during clinical trials to ensure that drugs produced are safe and cost-effective.

PRODUCT SHOWCASE: New Requirements for Injection Devices Make Advanced Testing Solutions Necessary

INDUSTRIALISATION

PRODUCT SHOWCASE: New Requirements for Injection Devices Make Advanced Testing Solutions Necessary

ZwickRoell showcases its advanced testing solutions for injection devices including pens, autoinjectors and on-body delivery systems.

Interview: Kymanox Executive Advisors Mathias Romacker, Fran DeGrazio & Paul Jansen

Interview: Kymanox Executive Advisors Mathias Romacker, Fran DeGrazio & Paul Jansen

Mathias Romacker, Fran DeGrazio and Paul Jansen sit down with Guy Furness, to discuss what it is that has driven Kymanox’s rapid rise in the drug delivery space and what makes the consulting company’s model so successful, as well as to share their expertise on a variety of topics in an illuminating discussion, including connectivity, how large and small drug developers engage with consultancies, 5 mL autoinjectors and the interface between drug primary packaging and delivery devices.

ANTICIPATING & MITIGATING CHALLENGES IN THE COMMERCIALISATION OF PREFILLED SYRINGES & INJECTION DEVICES – A TECHNICAL DRUG PRODUCT PERSPECTIVE

PREFILLED SYRINGES

Dr Andrea Allmendinger

ANTICIPATING & MITIGATING CHALLENGES IN THE COMMERCIALISATION OF PREFILLED SYRINGES & INJECTION DEVICES – A TECHNICAL DRUG PRODUCT PERSPECTIVE

Andrea Allmendinger and Hanns-Christian Mahler both at ten23 health, provide an insight into the challenges of integrated development of drug product and device design and fill-finish manufacturing operations.

BEING PREPARED FOR PHARMA INNOVATION IS KEY IN 2023

Victoria Morgan

West Pharmaceutical Services

BEING PREPARED FOR PHARMA INNOVATION IS KEY IN 2023

Victoria Morgan and Ana Marques Kuschel discuss three recent innovations that West Pharmaceutical Services has introduced to enable its partners to respond to specific market-driven challenges, from pandemic-driven pressures on fill-finish productivity to the underlying shift towards biologics and the accelerated growth of home-based treatment.

PATIENT JOURNEY AS THE FOUNDATION FOR HOLISTIC CONNECTED DEVICE DEVELOPMENT

PATIENT JOURNEY AS THE FOUNDATION FOR HOLISTIC CONNECTED DEVICE DEVELOPMENT

Mark Tunkel and Cécile Gross consider the development of connected drug delivery devices and identify how understanding the patient journey from diagnosis to treatment can be used as an early-stage decision-making tool.

DIGITAL HEALTH: ADDRESSING MODERN HEALTHCARE CHALLENGES WITH SENSORS

Dr Haykel Ben Jamaa

DIGITAL HEALTH: ADDRESSING MODERN HEALTHCARE CHALLENGES WITH SENSORS

Haykel Ben Jamaa explores why modern society needs digital health and how it is organised and implemented, with a focus on sensing technologies empowering digital health technologies.

ENGINEERING EXPERTISE: DESIGN FOR EXCELLENCE

INDUSTRIALISATION

Drew Jelgerhuis

Scherdel Medtec North America

ENGINEERING EXPERTISE: DESIGN FOR EXCELLENCE

Drew Jelgerhuis looks at how a design-for-excellence (DFX) systematic approach can help manufacturers achieve their objectives.

ISO 11608: WHAT THE NEW STANDARD MEANS FOR NIS MANUFACTURERS

Cambridge Design Partnership

ISO 11608: WHAT THE NEW STANDARD MEANS FOR NIS MANUFACTURERS

Steve Augustyn looks at ISO 11608 and what it means for needle-based injection device manufacturers.

DESIGN STRATEGY & CONSIDERATIONS FOR COMPRESSED GAS-POWERED DEVICE APPLICATIONS

DESIGN STRATEGY & CONSIDERATIONS FOR COMPRESSED GAS-POWERED DEVICE APPLICATIONS

Jack Auld discusses the potential of compressed gas as a power source for drug delivery devices, and explains how Altaviz can empower drug developers with the expertise to make full use of this exciting technology.

UNLIMITED POSSIBILITIES BY USING A GAS-PRODUCING DRY CELL

UNLIMITED POSSIBILITIES BY USING A GAS-PRODUCING DRY CELL

Marc Beutler and Matthias Meier discuss the myriad advantages of using a gas-producing dry cell as a drive system for injectable drug delivery devices, as compared with spring-based and electromechanical drives.

OFFERING A SMART AND SUSTAINABLE ON-BODY INJECTOR FOR CHRONICALLY ILL PATIENTS

OFFERING A SMART AND SUSTAINABLE ON-BODY INJECTOR FOR CHRONICALLY ILL PATIENTS

Cécile Gross discusses the unmet drug delivery needs in chronic diseases, and details how Nemera’s answer – the Symbioze^® on-body injector – fulfils these needs.

THE EVOLUTION OF WEARABLES – REPRESENTING THE VOICE OF THE ENTIRE ECOSYSTEM

West Pharmaceutical Services

THE EVOLUTION OF WEARABLES – REPRESENTING THE VOICE OF THE ENTIRE ECOSYSTEM

Lauren Orme, Victoria Morgan and Shari Krusniak consider the current landscape for on-body delivery systems and discuss how West Pharmaceutical Services is responding to the demands of various stakeholders.

ON-BODY DELIVERY SYSTEMS – NEWS AND TRENDS

ON-BODY DELIVERY SYSTEMS – NEWS AND TRENDS

Tom Oakley discusses the current state of play in the on-body delivery system space, reviews recent milestones and proposes directions for the future.

DEVELOPING AN ON-BODY PLATFORM FOR EFFECTIVE POST-OPERATIVE PAIN MANAGEMENT

Stevanato Group

DEVELOPING AN ON-BODY PLATFORM FOR EFFECTIVE POST-OPERATIVE PAIN MANAGEMENT

Paolo Golfetto and Sheldon Moberg discuss a collaboration between Stevanato Group and Bexson Biomedical that meets an urgent unmet patient need.

A NEW MEMS ENGINE FOR LARGE-VOLUME SUBCUTANEOUS INJECTORS

Dr Jiunn-Ru Lai

MicroMED Co Ltd

A NEW MEMS ENGINE FOR LARGE-VOLUME SUBCUTANEOUS INJECTORS

Jiunn-Ru Lai, Tsung-Chieh Cheng and Brian Li discuss how MicroMED’s Primary Actuator technology for driving high-volume, high-viscosity injection devices compares with current spring and motor technologies.

ACCELERATING DEVELOPMENT OF SUBCUTANEOUS DELIVERY OF LARGE-VOLUME BIOLOGICS

ACCELERATING DEVELOPMENT OF SUBCUTANEOUS DELIVERY OF LARGE-VOLUME BIOLOGICS

Tom Mayer discusses how Sonceboz’s vial-based on-body injector – the LVI-V – can expedite the launch of large-volume SC delivery of biologics by leveraging existing primary container technology, reducing associated risks and total cost of ownership.

KEY CONSIDERATIONS WHEN SPECIFYING A MOTION SYSTEM FOR WEARABLE INJECTORS

Dave Beckstoffer

KEY CONSIDERATIONS WHEN SPECIFYING A MOTION SYSTEM FOR WEARABLE INJECTORS

The reliable performance of a wearable drug delivery device is understandably paramount, so optimising the motion solution that drives it is crucial. Dave Beckstoffer discusses how best to achieve this and ensure the best match between the motion solution and the characteristics of the specified drug or drug range.

WEARABILITY AND USABILITY OF THE YPSODOSE 10 mL PATCH INJECTOR

WEARABILITY AND USABILITY OF THE YPSODOSE 10 mL PATCH INJECTOR

Jakob Lange discusses the results of a recently published study into the usability and wearability of the YpsoDose 10 mL patch injector, providing a summary of the insights acquired during the study.

MIKRON AUTOMATION: A LEADER IN THE COMPLEX ASSEMBLY OF ON-BODY INJECTORS

Jean-François Bauer

Mikron Automation

MIKRON AUTOMATION: A LEADER IN THE COMPLEX ASSEMBLY OF ON-BODY INJECTORS

Mikron Automation sets out its expertise in the assembly of on-body injectors, a field requiring exception precision and innovative approaches, as well as discussing how Mikron works with its partners from the very earliest stages of device development to help ensure projects are completed efficiently and successfully.

DRUG DELIVERY DEVICES THROUGHOUT THE DRUG DEVELOPMENT CYCLE

Dr Ori Ben-David

DRUG DELIVERY DEVICES THROUGHOUT THE DRUG DEVELOPMENT CYCLE

Ori Ben-David discusses the considerations that must be made over the course of injectable drug development and how Eitan Medical’s Sapphire™ and Sorrel™ platforms offer pharmaceutical companies a full suite of device tools from early discovery through to commercialisation.

FLEXIBLE CARE – ENABLE WEARABLE DELIVERY

Enable Injections

FLEXIBLE CARE – ENABLE WEARABLE DELIVERY

Jennifer Estep and Mehul Desai discuss the benefits for patients and healthcare providers of innovative subcutaneous delivery.

USING MAGNETIC SENSORS FOR METERING DRUG VOLUME IN WEARABLE INJECTORS

Coto Technology

USING MAGNETIC SENSORS FOR METERING DRUG VOLUME IN WEARABLE INJECTORS

Tim Reskerdiscusses the application of tunnelling magnetoresistive sensing technology to on-body injectors, including the vital function of accurately measuring the delivered dose, as well as other functions, such as powering on the device.

FROM SIMULATION TO SPRING SATISFACTION

INDUSTRIALISATION

Drew Jelgerhuis

Scherdel Medtec North America

FROM SIMULATION TO SPRING SATISFACTION

Drew Jelgerhuis discusses the power of simulation to enhance a drug delivery device design project, including faster development times and reduced costs.

INDUSTRIALISATION AND SCALE-UP OF DRUG DELIVERY DEVICES

INDUSTRIALISATION

Dr Barry McDermott

West Pharmaceutical Services

INDUSTRIALISATION AND SCALE-UP OF DRUG DELIVERY DEVICES

Barry McDermott and Shari Krusniak look at the manufacturing processes involved in bringing a new drug delivery system and formulation to market.

EMBRACING OPPORTUNITIES PRESENTED BY DIGITALISATION: USING DATA TO DRIVE PERFORMANCE

INDUSTRIALISATION

Otto Abildgaard

Stevanato Group

EMBRACING OPPORTUNITIES PRESENTED BY DIGITALISATION: USING DATA TO DRIVE PERFORMANCE

Otto Abildgaard and Sebastian Berninger-Lund review the four-stage process Stevanato has developed to bring improvements in time to market through optimised manufacturing.

HOLISTIC DEVELOPMENT & INDUSTRIALISATION OF DRUG DELIVERY DEVICES & COMBINATION PRODUCTS

INDUSTRIALISATION

HOLISTIC DEVELOPMENT & INDUSTRIALISATION OF DRUG DELIVERY DEVICES & COMBINATION PRODUCTS

Mark Tunkel and Niyati Sapatnekar discuss Nemera’s holistic approach to development and industrialisation.

TURNING CONNECTED DRUG DELIVERY PIPE DREAMS INTO REALITY

TURNING CONNECTED DRUG DELIVERY PIPE DREAMS INTO REALITY

Mindy Katz discusses the benefits of integrating homecare technologies that are patient centric and connected.

ADVANCEMENTS AND EVOLUTION OF POWER SOURCES IN DRUG DELIVERY

ADVANCEMENTS AND EVOLUTION OF POWER SOURCES IN DRUG DELIVERY

William Welch considers the evolution of compressed gas alternatives to spring power for single-use drug delivery devices.

Technology Showcase: CCBio’s Felice Dose

Technology Showcase: CCBio’s Felice Dose

CCBio introduces its wearable (on-body) injector, Felice Dose, which is capable of handling various drug volumes, concentrations and viscosities, as well as different injection speeds and delivery times.

SMART SOLUTIONS TO REDUCE CARBON FOOTPRINT

SMART SOLUTIONS TO REDUCE CARBON FOOTPRINT

Rob Doorakkers and Geert van Amstel discuss why the company decided to become carbon neutral, how it is working to make injection moulding more sustainable and how the organisation is minimising its impact on the environment.

HOW MINIATURISED LIQUID FLOW SENSORS ARE REVOLUTIONISING SUBCUTANEOUS DRUG DELIVERY

HOW MINIATURISED LIQUID FLOW SENSORS ARE REVOLUTIONISING SUBCUTANEOUS DRUG DELIVERY

Andreas Alt and Susanne Pianezzi describe the drivers accelerating industry trends towards both wearable subcutaneous injection devices and connecting such devices to monitor patient dosing, providing a number of benefits.

MATERIAL SELECTION FOR NEXT-GENERATION CONNECTED MEDICAL ELECTRONICS

Miriam Kingsley

MATERIAL SELECTION FOR NEXT-GENERATION CONNECTED MEDICAL ELECTRONICS

Miriam Kingsley, Marcus Jarman-Smith and Thomas Billings highlight the growing array of applications for high-performance polymers in electronic and connected medical devices and how proper material selection is crucial, providing a guide to successful material selection, going on to showcase its APTIV™ PEEK polymer film, which is well suited to meet the specific demands of next-generation connected medical devices.

ROUNDTABLE: ALLIANCE TO ZERO

Sebastian Gerner

Alliance to Zero

ROUNDTABLE: ALLIANCE TO ZERO

Sebastian Gerner, Robert O’Beirn and Sabrina Gérard talk with ONdrugDelivery about the Alliance to Zero, an association for pharma and biotech supply chain companies that aims to facilitate the transition of the pharma sector to compliance with net-zero emissions.

RELENTLESS PRECISION DELIVERS VALUE IN NEEDLE-HANDLING AUTOMATION FOR COMBINATION PRODUCTS

INDUSTRIALISATION

William Jaworski

Mikron Automation

RELENTLESS PRECISION DELIVERS VALUE IN NEEDLE-HANDLING AUTOMATION FOR COMBINATION PRODUCTS

William Jaworski and Michael Gunner discuss the precision and complex manipulation of needles required for the latest combination medical products.

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