EARLY INSIGHT

ACQUIRING A LIQUID BIOPSY INCIDENTAL TO INTRAVITREAL INJECTION

Alexandre Tumlinson introduces Twenty/Twenty Therapeutics' VitreoDx injection system to address emerging trends in intravitreal therapeutics.

SAY “NO MORE” TO NEEDLES: NEEDLE-FREE SELF-INJECTION TECHNOLOGY FOR PAINLESS, BETTER CARE

Alina Su discusses the need for improved and optimised remote healthcare to meet current challenges in the industry, and introduces Telosis, the company’s patent-pending connected needle-free injection device that is poised to provide answers to these challenges.

MISTGO<sup>®</sup> – A NEW MICRODOSING EYE MEDICATION DELIVERY SYSTEM

MISTGO^® – A NEW MICRODOSING EYE MEDICATION DELIVERY SYSTEM

Rie Saabye and Morten Jacobsen discuss the benefits of a new microdosing eye medication delivery system for chronic ophthalmic diseases, such as dry eye disease and glaucoma.

CREATING A PLATFORM FOR NEBULISATION OF A WIDE RANGE OF DRUG TYPES AND FORMULATIONS

Dr Elijah Nazarzadeh

CREATING A PLATFORM FOR NEBULISATION OF A WIDE RANGE OF DRUG TYPES AND FORMULATIONS

Elijah Nazarzadeh and John Pritchard introduce Nebu~Flow – a novel class of nebuliser technology that represents a major step in the ability to deliver drugs efficiently to the lungs. overcoming the limitations of current systems and unlocking the potential of the inhalation route, including for systemic delivery.

CLIPhaler – INHALATION DEVICE DESIGN REDUCED TO THE MAXIMUM

Dr Klaus-Dieter Beller

CLIPhaler – INHALATION DEVICE DESIGN REDUCED TO THE MAXIMUM

Klaus-Dieter Beller discusses the advantages of the inhalation route of administration, how his principle of design simplicity has informed the design of novel inhalation devices and introduces CLIPhaler, his latest and simplest device.

NO TYPE: AN APP TO PREDICT PATIENTS’ LIKELIHOOD TO TAKE MEDICATION AS PRESCRIBED

NO TYPE: AN APP TO PREDICT PATIENTS’ LIKELIHOOD TO TAKE MEDICATION AS PRESCRIBED

Louisa Harvey, Alper Hulusi, Bjarki Holm and Stefan Olafsson introduce their quick and accessible app for identifying whether or not a patient is likely to take their medication as prescribed.

PERSONALISED AEROSOL LOADING AND MANAGEMENT (PALM): A HANDHELD DEVICE FOR AEROSOL DRUG DELIVERY

Dr Jason Brenker

Monash University

PERSONALISED AEROSOL LOADING AND MANAGEMENT (PALM): A HANDHELD DEVICE FOR AEROSOL DRUG DELIVERY

Jason Brenker, Tuncay Alan and Daniela Traini introduce the PALM – Personalised Aerosol Loading and Management – device, a unique, advanced drug delivery device enabling personalised delivery of aerosols to improve the efficacy of inhaled medications and patient compliance.

A NEW PLATFORM FOR SUPRACHOROIDAL DRUG DELIVERY USING STANDARD NEEDLES

Timo Kangastupa

A NEW PLATFORM FOR SUPRACHOROIDAL DRUG DELIVERY USING STANDARD NEEDLES

Timo Kangastupa discusses the potential of the suprachoroidal space for highly effective, specifically targeted drug delivery to the choroid and retina, and how Visionisti’s technology simplifies and standardises the procedure, enabling the use of standard commercially available needles for suprachoroidal delivery.

PHARMACOKINETIC MODELS: INDISPENSABLE TOOLS FOR OPHTHALMIC DRUG DEVELOPMENT

Dr Eva M del Amo

University of Eastern Finland DrugTech

PHARMACOKINETIC MODELS: INDISPENSABLE TOOLS FOR OPHTHALMIC DRUG DEVELOPMENT

Eva del Amo presents an overview of pharmacokinetic models for ophthalmic drugs, and discusses the value of these models for future drug development in the sector.

3D-PRINTED HOLLOW MICRONEEDLES: A NEW FRONTIER FOR TRANSDERMAL DRUG DELIVERY

Dr Dimitrios Lamprou

Queen's University Belfast

3D-PRINTED HOLLOW MICRONEEDLES: A NEW FRONTIER FOR TRANSDERMAL DRUG DELIVERY

Dimitrios Lamprou and Essyrose Mathew discuss the potential of 3D-printed hollow microneedles for transdermal drug delivery.

USING BLOCKCHAIN AND DATA ANALYTICS FOR IMPROVED MEDICAL CANNABIS EFFICACY

Global Cannabis Applications Corp

USING BLOCKCHAIN AND DATA ANALYTICS FOR IMPROVED MEDICAL CANNABIS EFFICACY

Brad Moore and Tim Morch describe GCAC’s technology offering, a blockchain-based software system that is able to transparently track the progress of medical cannabis from cultivation through to consumption.

ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES

Dr Antonio Costa

ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES

Antonio Costa discusses the use of lipid nanoparticles in the modern drug delivery industry and introduces the DIANT system for the continuous processing of nanoparticles with integrated process analytical technology, which can provide the quality required for these injectable, complex formulations.

SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY

Mr Richard Joye

SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY

Richard Joye and Tim Morch discuss the advantages of using dissolvable microneedles for the delivery of vaccines, particularly in regards to storage and transport, and introduce SeriTech’s fast-detaching dissolvable microneedle technology.

GASTRIC FLOATING MICROCAPSULES FOR THE MANAGEMENT OF PARKINSON’S DISEASE

Dr Sashi Kesavapany

GASTRIC FLOATING MICROCAPSULES FOR THE MANAGEMENT OF PARKINSON’S DISEASE

Kaarunya Sampathkumar, Joachim Loo and Sashi Kesavapany discuss current treatments for Parkinson’s disease and introduce an extended-releasing technology for polypharmacy oral formulations.

NEW ENGINE FOR PRIMARY CONTAINER INJECTORS: A POWERFUL MICRO LINEAR ACTUATOR

MicroMED Co Ltd

NEW ENGINE FOR PRIMARY CONTAINER INJECTORS: A POWERFUL MICRO LINEAR ACTUATOR

Brian Li, Jiunn-Ru Lai, Tsung-Chieh Cheng, Kuang-Hsiang Cheng, Min-Ru Wang, Chia-Chi Tina Feng, and Wen-Chi Huang introduce the company’s new engine for primary container injectors, the Primary Actuator, which targets the unmet needs in the autoinjector and wearable injector market as the market shifts towards large injection volumes.

AN ANGLED MICRONEEDLE PATCH FOR ENHANCED DRUG AND VACCINE DELIVERY

Dr Nicky Bertollo

AN ANGLED MICRONEEDLE PATCH FOR ENHANCED DRUG AND VACCINE DELIVERY

Nicky Bertollo, Ronan Byrne and Andrew Muddle introduce Pharma Latch – a user-centric angled microneedle patch technology. They discuss its key benefits, such as dramatically increased payload potential, precision, low cost and variable patch-wear times, and highlight how Pharma Latch has the potential to overcome many of the limitations of existing routes of administration for therapeutics and vaccines.

MEDICSEN: NEEDLE-FREE SMARTPATCH FOR PAINLESS DRUG DELIVERY

Dr Eduardo Jorgensen

MEDICSEN: NEEDLE-FREE SMARTPATCH FOR PAINLESS DRUG DELIVERY

Eduardo W Jørgensen, Juan César de Mercado and José Carlos Montesinos describe the Smartpatch, a novel technology for subcutaneous delivery of drugs via a comfortable, pain-free patch using sonophoresis, based on Medicsen’s patented miniaturised ultrasound technology.

EPIWATCH: A NOVEL LIFE-SAVING MICRO AUTOINJECTOR IN A SMART WATCH

EPIWATCH: A NOVEL LIFE-SAVING MICRO AUTOINJECTOR IN A SMART WATCH

Amber Witteman, Thijs Roebers and Dirk-Jan Opstelten introduce the company’s patented innovation, a wearable autoinjector customised to fit the wrist.

INNOVATIVE DRUG-ELUTING ADHESIVES: APPLICATION IN CHRONIC RHINOSINUSITIS

Dr Maria Pereira

INNOVATIVE DRUG-ELUTING ADHESIVES: APPLICATION IN CHRONIC RHINOSINUSITIS

Maria Pereira, Elise DeVries and Camille Legros introduce novel applications in the treatment of chronic rhinosinusitis for the company’s programmable synthetic polymers and an associated delivery device.

A FLEXIBLE, MODULAR PLATFORM TO DISRUPT THE BLOCKBUSTER MANUFACTURING MODEL

BiologIC Technologies

A FLEXIBLE, MODULAR PLATFORM TO DISRUPT THE BLOCKBUSTER MANUFACTURING MODEL

Nick Rollings, Colin Barker and Richard Vellacott discuss the drug delivery scenario in the advanced therapy (AT) era, examining how the current slow-moving blockbuster treatment model is making way for a fast-moving, patient-focused era of personalised medicine

REDUCING VASCULAR MORTALITY IN PATIENTS WITH SUSPECTED ACUTE MI

Mark Stansfield

REDUCING VASCULAR MORTALITY IN PATIENTS WITH SUSPECTED ACUTE MI

Mark Stansfield and Kambiz Yadidi discuss initial results of their pilot Phase I clinical study of dry powder inhalation formulation of aspirin for the treatment of acute myocardial infarction.

PERSONALISING DRUG PRODUCTS USING 3D PRINTING

Sarah Trenfield

PERSONALISING DRUG PRODUCTS USING 3D PRINTING

Sarah Trenfield and Abdul Basit look at the potential applications of 3D-printing technology to create personalised drug therapies in fields such as multiple drug therapy and paediatric/geriatric care and introduce FabRx’s 3D-printing system, which can produce formulations to suit a variety of situations.

SKIN-MOUNTABLE FLEXIBLE NEEDLE PATCH FOR MINIMALLY INVASIVE CONTROLLED DRUG DELIVERY

Dr Chi Hwan Lee

Weldon School of Biomedical Engineering

SKIN-MOUNTABLE FLEXIBLE NEEDLE PATCH FOR MINIMALLY INVASIVE CONTROLLED DRUG DELIVERY

Chi Hwan Lee and Eun Kwang Lee introduce a skin-mountable flexible needle patch and discuss its applications in non-invasive drug delivery applications.

TARGETING DRUGS TO DISEASED OCULAR CELLS

Frazer P Coutinho

TARGETING DRUGS TO DISEASED OCULAR CELLS

Frazer Coutinho, Colin Green and Ilva Rupenthal discuss the targeted delivery of ocular therapeutics to diseased cells, using the cell-penetrating peptide, Xentry.

CITRUS FRUITS INSPIRE THE NEXT GENERATION OF AIRBORNE DRUG DELIVERY

Dr Andrew K Dickerson

Fluids and Structures (FaST) Laboratory

CITRUS FRUITS INSPIRE THE NEXT GENERATION OF AIRBORNE DRUG DELIVERY

Andrew Dickerson discusses recent research undertaken by his team into the mechanics of liquid microjets created naturally by citrus fruits, and how they could be the key to a new design of drug delivery device.

ELECTROSPINNING: A PROMISING APPROACH TO CONTINUOUS MANUFACTURING FOR PHARMACEUTICALS

Dr Blair Brettmann

Georgia Institute of Technology

ELECTROSPINNING: A PROMISING APPROACH TO CONTINUOUS MANUFACTURING FOR PHARMACEUTICALS

Blair Brettmann discusses the present advantages and challenges, as well as the future potential, of electrospinning as a continuous manufacturing technique for the pharmaceutical industry.

LISTEN TO YOUR INHALER, IT MIGHT BE TELLING YOU SOMETHING

Dr Kian Min Lim

LISTEN TO YOUR INHALER, IT MIGHT BE TELLING YOU SOMETHING

Kian Min Lim and David Harris discuss how tailored algorithms can accurately detect inhalers’ acoustic signatures, effectively adding connectivity without having to add a chip to the inhaler.

AN INTRADERMAL PLATFORM BUILT FOR INDUSTRY AND PATIENTS

AN INTRADERMAL PLATFORM BUILT FOR INDUSTRY AND PATIENTS

Moe Wehbe, Iman Mansoor and Sahan Ranamukha discuss the potential of intradermal injection for modern medicines and its advantages over the subcutaneous route.

SIMPLIFIED DRUG AND VACCINE DELIVERY USING MICRON’S MICRONEEDLE PATCH

Dr Mark Prausnitz

Micron Biomedical

SIMPLIFIED DRUG AND VACCINE DELIVERY USING MICRON’S MICRONEEDLE PATCH

Devin V McAllister, Sebastien Henry and Mark Prausnitz introduce the company’s dissolving microneedle patch technology, which has global potential, including in the developing world, across a range of vaccine and therapeutic applications.

BREAKTHROUGH NANOTECHNOLOGY ENHANCES DELIVERY TO THE FRONT AND BACK OF THE EYE

Dr Robert Langer

Kala Pharmaceuticals

BREAKTHROUGH NANOTECHNOLOGY ENHANCES DELIVERY TO THE FRONT AND BACK OF THE EYE

Hongming Chen and Robert Langer discuss applications of the company’s Mucus Penetrating Particle nanotechnology in ophthalmic drug delivery.

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